The synergistic effect of platelet-rich fibrin (PRF) and bone substitutes
DOI:
https://doi.org/10.51126/revsalus.v3i2.132Keywords:
biomaterials, bone repair, ceramic, fibrinAbstract
The purpose of this study was to perform a narrative review on the synergistic effect of the combination of PRF and
bone grafts. The literatre data reports that the mixture of PRF to bone substitutes accelerates bone formation in small
bone defects. There is no consensus in the literature regarding the effects on larger bone defects. The addition of PRF allows the use of a low amount of particulate grafts, thus reducing treatment costs. However, more randomized clinical studies are needed to validate these results.
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